Production and characterization of alginate-starch-chitosan microparticles containing stigmasterol through the external ionic gelation technique
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چکیده
منابع مشابه
The effect of chitosan molecular weight on the properties of alginate/ chitosan microparticles containing prednisolone
Purpose: The aim of the present study was to investigate the effect of chitosan molecular weight on size, size distribution, release rate, mucoadhesive properties and electrostatic bonding of alginate/chitosan microparticles containing prednisolone Methods: Three mucoadhesive alginate/chitosan microparticle formulations, f1, f2 and f3, were prepared using low, medium and high chitosan molecular...
متن کاملIn situ rheological measurements of the external gelation of alginate
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متن کاملEvaluation of furosemide-loaded alginate microspheres prepared by ionotropic external gelation technique.
Alginate microspheres containing furosemide were prepared by the ionotropic external gelation technique using Ca2+, Al3+ and Ba2+ ions. The incorporation efficiency of the prepared microspheres ranged between 65% and 93%. The effect of sodium alginate concentration, cross-linking ions and drying conditions was evaluated with respect to entrapment efficiency, particle size, surface characteristi...
متن کاملMechanical properties of alginate hydrogels manufactured using external gelation.
Alginate hydrogels are commonly used in biomedical applications such as scaffolds for tissue engineering, drug delivery, and as a medium for cell immobilisation. Multivalent cations are often employed to create physical crosslinks between carboxyl and hydroxyl moieties on neighbouring polysaccharide chains, creating hydrogels with a range of mechanical properties. This work describes the manufa...
متن کاملPreparation of Chlorpheniramine Maleate-loaded Alginate/Chitosan Particulate Systems by the Ionic Gelation Method for Taste Masking
BACKGROUND Chlorpheniramine maleate (CM) is widely used as an antihistaminic drug but it is very bitter and as yet no mouth dissolving/disintegrating taste-masked preparation that might be useful for pediatric and geriatric patients is available in the market. OBJECTIVES The purpose of this research was to mask the bitter taste of CM by formulating microspheres of the taste-masked drug. MAT...
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2013
ISSN: 1984-8250
DOI: 10.1590/s1984-82502013000300015